Medical marijuana is a safe and effective option for the treatment of symptoms that are caused by chronic health issues. With improvements medical marijuana delivery into the body, it has become easier to treat common symptoms and discomfort resulting chronic pain, inflammation, anxiety, depression and epileptic seizures with speed and ease. Cannabis based medicines are now at the forefront of the pharmacological world and the use for cannabis will continue to grow in the future.
Chronic Pain and Inflammation
Mary E Lynch, et al. suggest that the use of cannabinoids are a safe and effective treatment option for chronic pain conditions such as rheumatoid arthritis, fibromyalgia, and neuropathic pain. They demonstrated an enhanced analgesic effect and several reported significant improvements in the quality of sleep without serious side effects.
Cannabinoids bind to 4 different subtypes of receptors found in the central nervous system and the peripheral nervous system. These subtypes include CB1, CB2, WIN and the anandamide receptor. CB1 receptors are found in tissues associated with pain perception such as the central nervous system, the spinal column and the periphery nervous system which include the nerves. Endocannabinoid compounds, found naturally in the body, bind to the CB1 receptor to decrease the sensation of pain and inflammation of the tissues in the body. The CB1 receptor regulates the release or blocks the release of neurotransmitters (serotonin, dopamine, L-glutamate, GABA, acetylcholine and noradrenaline) from neurons and nerve cells. J Manzanares, et al. confirm that there are receptors and endocannabinoids that exist in pain circuits. They have been found from the peripheral nerve endings in all regions of the body up to the brain. T
Anxiety and Depression
Anxiety and disorders related to anxiety affect a large percentage of our society.
Cannabidiol (CBD) has been proven to counteract anxiety without the side effects people would get by taking prescription drugs such as Zoloft and Xanax.
CBD acts on the serotonin system in the brain. The molecule binds to the 5-HT1A receptor, a type of serotonin receptor located on surface of neurons. Researchers have found that CBD boosts transmission of 5-HT1A resulting in an increase in serotonin production. The results were more dramatic when medical marijuana delivery was through smoking or when CBD was given through injection.
A study conducted by Esther M. Blessing, et. al. suggests that CBD be used as a treatment for anxiety disorders such as post-traumatic stress disorder, generalized anxiety disorder, social anxiety disorder, panic disorder, and obsessive–compulsive disorder. The molecule interacts with several cellular receptors that have been determined to control fear anxiety and fear related behaviors.
Research suggests that cannabidiol, when taken daily for up to 18 weeks, can decrease the amount of seizures in some people. An article written in Scientific American reports that treatment with cannabis reduces epileptic seizures that are considered to be severe. Children with this rare childhood epilepsy were given CBD daily for 14 weeks. Their average incidence of convulsive seizures were reduced to from 12.4 to 5.9 seizures per month.